We are in relentless pursuit of breakthroughs that change patients' lives. We create innovations daily to make the world a healthier place. It was Charles Pfizer's original vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best talent, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that improve patients' lives—powers everything we do and shows our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and represents the value we work to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We live our purpose by seeking the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.